Understanding Migraine and Neurological Disorders
When traditional medications and therapies provide limited relief, Transcranial Magnetic Stimulation (TMS) offers a non-invasive, drug-free alternative that targets the root cause: abnormal brain activity.
Migraines are believed to begin with a phenomenon called cortical spreading depression — a wave of abnormal brain activity that triggers headache and aura symptoms.
Research has shown that single-pulse TMS (sTMS) can disrupt cortical spreading depression, reducing migraine severity and duration.
In clinical studies, patients treated with sTMS during a migraine aura experienced faster pain relief and decreased need for rescue medication.
Animal model studies confirm that sTMS effectively interrupts cortical spreading depression, supporting its use as an acute migraine therapy.
To make treatment accessible beyond the clinic, portable sTMS devices have been developed, allowing patients to manage migraine attacks conveniently at home.
While sTMS helps stop migraines once they begin, repetitive TMS (rTMS) is being explored as a preventive option.
By modulating brain excitability and neurotransmitter activity, rTMS may help reduce migraine frequency, intensity, and overall disability.
Though research is still evolving, early clinical studies show that stimulating the motor and dorsolateral prefrontal cortices can lead to measurable improvement in chronic migraine sufferers who have not responded to medications.
Beyond migraine management, TMS is also being studied and used off-label for a variety of neurological and pain conditions, including:
By improving brain connectivity and neuronal function, TMS offers a non-invasive approach to restoring neurological balance across these conditions.
At Dr. Gupta’s Sleep, TMS & Wellness Psychiatry in Great Neck, NY, we use advanced neuromodulation therapies to help you find relief and restore balance to your brain and life.